People want to look better with as little as possible downtime. Although a quick fix is not possible for severe wrinkles, newer treatment options such as fractional lasers and fractional radiofrequency are available to slow down the aging aspects that affect the face, neck, décolleté, and the back of the hands. Vampire Facelift is a name for a non-surgical cosmetic procedure involving the injection of platelet-rich plasma (PRP) derived from a patient's blood back into multiple areas of the skin of their face to treat wrinkles and "rejuvenate" the face. Platelets have essential growth factors that, when secreted, handle tissue regeneration and rejuvenation, increase collagen production, recruit other cells to the injury site, induce cell differentiation, and extracellular matrix formation. It has an anti-inflammatory effect that will speed up healing time and ease recovery time after resurfacing procedure. In a new approach, Prof uses fractional ablative lasers to overcome the epidermal barrier and increase topical agents' penetration as laser-assisted drug delivery (LADD). Prof Moawad offers his patients a full-face fractional CO2 laser or fractional radiofrequency (FRF) to make tiny holes into the skin to overcome the stratum corneum to enhance PRP and nanofat. The results are doubles. You will enjoy the rejuvenating effect of fractional skin resurfacing systems and the regenerative effect of growth factors and stem cells present in PRP and nanofat.