A variety knows fat transfer of names, of which the commonly used are fat transfer, fat injection, and autologous fat grafts. The word autologous means material (fat) is harvested from one area and donated to another in the same individual. Fat transfer has become an increasingly important method of facial rejuvenation both as a standalone procedure and in combination with traditional rejuvenation methods, like face-lifting, brow lifting, and Blepharoplasty. Fat transfer is particularly suited for restructuring the proportion of the face. Typical facial structures can also be aided by adding constructive elements to correct a broad range of perceived facial deficiencies. For example, a stronger jawline creates a youthful, more powerful-looking face; eliminating the hollowness of lower lids helps reduce that tired, sad appearance; and fuller lips create a more youthful, attractive appearance. Other indications include congenital, traumatic defects, or surgical defects and scars. Nanofat is applicable in a wide range of indications to improve the skin quality; trophic skin changes caused by age and sun damage, pigmentary skin conditions, and scarring Non-facial areas such as the neck, the décolleté area, and the hands can also greatly benefit from the use of nanofat grafting, sometimes in combination with microfat.