Today, fat grafting has gained an essential role in the plastic surgeon’s armamentarium as a safe and easy-to-use tool for an experienced surgeon. Fat grafting has the advantage of using autologous tissue that allows natural reshaping and volume augmentation and the double benefit of removing unwanted fatty deposits in donor sites by liposuction. The technique of autologous fat-graft injection to the breast is applied for the correction of breast asymmetry; of breast deformities; congenital defect correction” micromastia, and tuberous breast deformity, breast reconstruction: for post-mastectomy breast reconstruction (as a primary and as an adjunct technique; trauma-damaged tissues (blunt, penetrating), disease (breast cancer), explanation deformity (empty breast-implant socket).); for the improvement of soft-tissue coverage of breast implants and the aesthetic enhancement of the bust.